DECODING THE DUAL RECOGNITION MECHANISM OF THE GLUCOCORTICOID RECEPTOR FOR DNA AND RNA: SEQUENCE VERSUS SHAPE

Decoding the dual recognition mechanism of the glucocorticoid receptor for DNA and RNA: sequence versus shape

Abstract Transcription factors (TFs) Baby Wash regulate eukaryotic transcription through selective DNA-binding, can also specifically interact with RNA, which may present another layer of transcriptional control.The mechanisms of the TFs-DNA recognition are often well-characterised, while the details of TFs-RNA complexation are less understood.Here

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